Monday, June 22, 2020

To help you understand urine protein

What is urine protein?

Urine examinations of patients with nephropathy often show urinary protein +, which is an important indicator for the diagnosis and prognostic evaluation of nephropathy. Urine protein is related to the destruction of glomerular filtration membrane structure and protein leakage, but in some cases there will be urine protein, such as strenuous exercise, high fever, severe infection, high protein diet, nutcracker phenomenon, etc.

Is there urine protein that is not a cause of kidney disease?

1. Urine protein after exercise

Transient urinary protein may appear after high-dose exercise. Urine protein does not exceed 0.5 to 1 gram in 24 hours. Urine protein disappears after resting. It is more common in young adults, after high fever, long march, strong physical labor, and high protein diet.

2. Postural urine protein

When standing for a long time or lordosis posture, urine protein increases, urine protein decreases or disappears after supine rest, more common in slender young people. Repeated postural proteinuria, attention should be paid to the nutcracker phenomenon (ie, left renal vein compression syndrome, due to the compression of the left renal vein by the aorta and superior mesenteric artery).

What are the urine protein related tests?

1. Qualitative inspection

It is best to leave the first urine in the morning, the morning urine is the most concentrated, and can exclude postural proteinuria, discard the previous section, leave the middle section of urine, urine routine qualitative examination is only the initial screening.

2. Quantitative inspection

Take 24 hours of urine, mix and record the total amount, take 10ml of urine and send to check the 24h urine protein quantification.

3. Special inspection

Such as urine fixed electrophoresis, urine light chain quantification, etc., should cooperate with blood biochemistry, immunity, urinary system B-ultrasound and other tests.

Is long-term urine protein harmful to the human body?

Long-term loss of protein in the urine will reduce the protein content in the body, reduce the protein in the blood, reduce the osmotic pressure of the plasma, and cause edema caused by the water entering the tissue. Decreased blood protein, increased liver synthesis, and abnormal lipid metabolism, causing hyperlipidemia. Severe hypoproteinemia, hypercoagulable state for a long time may even form thrombosis.

Kidney disease is not easy to find. After finding an abnormal urine test, you must consult a medical doctor in time. Proteinuria is an independent risk factor for glomerular sclerosis and renal insufficiency. It should be paid attention to so as not to delay the diagnosis and miss the best time for treatment.

How to prevent urine protein?

Pay attention to avoid excessive protein diet, low-salt diet, regularly check urine routine, family history of diabetes, hypertension, gout, cardiovascular and cerebrovascular diseases, nephropathy, should check urine routine every six months to 1 year to avoid kidney damage drugs, such as Antipyretic and analgesic drugs, some antibiotics and prescriptions and Chinese patent medicines of unknown ingredients.

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